New biochemical method accurately diagnoses autism in children

19 March, 2017, 15:28 | Author: Eloise Marshall
  • Breakthrough? The new method designed by New York's Rensselaer Polytechnic Institute is the first to analyze metabolic biomarkers that come before behavioral changes

Autism Speaks states that "autism spectrum disorder" consists of varying conditions involving behavioural problems, issues with social skills, speech and nonverbal communication, and repetitive behavior. The fundamental causes of ASD still remain a mystery, but it is understood that early diagnosis can lead to more effective treatment and management as a child develops.

According to the findings of a recent research, an experimental blood test can help in detecting early signs of autism in children. But researchers have struggled to translate these into new diagnostic tools.

Although ASD affects about 1.5 percent of all children, its exact cause remains unknown, and diagnosis requires many doctors specialising in a number of different disciplines.

The number of ASD diagnoses has drastically increased over the past few decades, and in the US, the estimates show a 30 percent increase in the number of children with ASD compared with previous years. However, most of the current diagnosis practices and psychometric tools rely purely on the detection of behavioral signs.

A blood test for autism has been developed at Rensselaer Polytechnic Institute. While prior research often focused on single metabolites or biomarkers, this new process measures 24 separate metabolites from a blood sample and, through a complex algorithm, can allegedly determine whether an individual is on the autism spectrum.

According to RPI News, the researchers were investigating patterns of various metabolites and found out that there are significant differences between the metabolites of children with ASD and to those who are neurotypical. The children were between 3 and 10 years old.

These are produced by chemical reactions known as FOCM (folate-dependent one-carbon metabolism) and TS (transulfuration).

Both of these substances have previously been shown to become altered in people with an increased risk of ASD.

Hahn's study, however, is based on multivariate statistical models that enabled his team to classify children with autism based on their neurological status.

"The models developed herein have much stronger predictability than any existing approaches from the scientific literature". By using the algorithm, the prediction about the data from the omitted individual correctly identified the 97.6 percent of children with autism, and 96.1 percent of those neurotypical participants.

"These differences allow us to categorize whether an individual is on the Autism spectrum", said Juergen Hahn, lead author, systems biologist, professor, and head of the Rensselaer Department of Biomedical Engineering.

Recommended:

  • Pope Francis to visit Cairo in April

    Pope Francis to visit Cairo in April

    Christians, mostly Orthodox Copts, account for about 10 percent of Egypt's population, which is overwhelmingly Sunni Muslim. President Sisi greatly appreciates Pope Francis, his moral stature and courage in addressing worldwide issues.
    Donald Trump Billboard in Arizona Has Caused Artist to Get Death Threats

    Donald Trump Billboard in Arizona Has Caused Artist to Get Death Threats

    Fiorito says she expects to receive some negative feedback from Trump supporters. Instead of an American flag, Trump is wearing a Russian flag lapel pin.
    Samsung Galaxy S8 'maybe' feature facial-recognition for mobile payments

    Samsung Galaxy S8 'maybe' feature facial-recognition for mobile payments

    Meanwhile, those in the United Kingdom will be able to get their hands on the new Samsung Galaxy Tab S3 on Friday, March 31. Nearly every single detail is known about the device, even though we are still ten days away from the release event.
  • United Kingdom denies helping Obama spy on Trump

    On March 9, Comey briefed Nunes, Schiff, Ryan, Burr, Warner and three other top congressional officials on the same intelligence. The phrasing of the statement left open the possibility that tenants or employees working in the tower may have been monitored.

    'Police operation' underway at Paris' Orly airport

    Intending travellers who had not yet reached the airport were warned: "Ongoing special operation by the police at Paris-Orly". The French Interior Minister, Bruno Le Roux, confirmed reports that claimed that Belgacem shot an officer earlier that day.
    Huawei announces P10 Lite smartphone

    Huawei announces P10 Lite smartphone

    According to PC Advisor , the Huawei P10 Lite is available for pre-order on EE, Vodafone , and Carphone Warehouse . Unsurprisingly, the Huawei P10 Lite is getting a 3,000 mAh battery, slightly smaller than the flagship's 3,200 mAh.
  • 'Buhari receives report on Magu's rejection from Senate'

    'Buhari receives report on Magu's rejection from Senate'

    All these will only undermine democracy and constitutionalism in our country", he said. "Now the EFCC chairman came and he did not pass the screening".
    Tripura: 3 tribals killed in BSF firing

    Tripura: 3 tribals killed in BSF firing

    Government offices, banks and financial institutions did not register any attendance. The local CPI (M) unit also enforced a dawn-to-dusk bandh in Sabroom sub-division.
    March Madness: Arizona easily handles North Dakota, 100-82

    March Madness: Arizona easily handles North Dakota, 100-82

    While Arizona Wildcats are used to seeing coach Sean Miller drenched in sweat, it quickly became clear that Twitter was not. In all, five Wildcats finished in double figures. "Tonight we had to get stops".
  • 6N: Gilchrist replaces injured Richie Gray in Scotland pack

    6N: Gilchrist replaces injured Richie Gray in Scotland pack

    Scotland are huge odds-on favourites with Sky Bet to end their Six Nations campaign with a win against outsiders Italy . VERN COTTER won't allow the emotion of his final game in charge of Scotland to get in the way of the Italian job.

    Progressives Attempt to Divide Trump Administration on Climate Policy Funding

    The National Institutes of Health faces a $5.8 billion cut, also 18% from its current budget, to $25.9 billion in total. There's another complication: Thanks to the landmark 2007 Supreme Court decision, MA vs.
    Disney's Mulan Will Be a Girly Martial Arts Movie, Not a Musical

    Disney's Mulan Will Be a Girly Martial Arts Movie, Not a Musical

    Director Niki Caro confirmed that, at the moment, the film will not feature any of the original songs or even new ones. Or if it would be more like the Jungle Book, which had just a few songs sprinkled in here and there.


Popular

How to watch, tv channel, scores and updates, who will win?
Our kids are young, unsure, and it's on the biggest stage of the whole year. "I don't think we're afraid of anybody". The team makes too many mistakes and looks lost too often on the road. "They won't forget what they've done".

Nude pictures and videos stolen and shared without her consent
WWE star Paige is back in the hot seat after being victimized by hackers, with her nude photos and private videos leaked online. As per Comic Book , the WWE star's family members have continued to support her, despite the rough road that Paige is facing.

Farmer friendly Maharashtra Budget passed in legislature amidst pandemonium
Value-Added Tax on soil testing kits and Milk testing kits has also been brought down to zero from the earlier 13.5%. The state has also made provision of Rs 200 crore for developing community farming and developing farmer clusters.

What Does a 31% Cut to EPA Budget Mean for Environmental Managers?
The National Science Foundation, which gives out more than $7 billion in research grants annually, is not mentioned in the budget. More than 50 environmental programs would be eliminate under the spending plan , including the Energy Star initiative.

G20 financial chiefs agree open trade is key to growth-Schaeuble
Officials may continue to seek greater consensus on the trade stance between now and the G-20 leaders' summit in Hamburg in July. But trade deals that now exist are not always balanced, he said, warning that Washington will not hesitate to renegotiate them.