Avon and Somerset Police said: "The closure is likely to be in place for a considerable amount of time and we'd ask people to avoid the area".
"The motorway is now closed in both directions between J16 and J14 and emergency services are working at the scene".
Director Simon Ellis of Avon and Somerset Police said the protect and recuperation operation was "careful work" and that various preoccupations stayed set up.
Four people have died and a woman and two children are seriously ill in hospital after a lorry smashed through the central reservation on the M5.
Officers said a lorry travelling southbound crashed through the central reservation and hit at least two vehicles heading the opposite way.
"There were many people with blood on their bodies and then the vehicle that had been forced down into the ditch with the lorry was surrounded by many men who were trying their hardest to get out the people inside... the emergency services were incredible but honestly it was the worst crash I've ever seen".
He said three miles of traffic trapped between the junctions was still being cleared via one lane of the northbound carriageway. One vehicle was said to have been completely destroyed.
Witnesses reported seeing people lying by the side of the road as members of the public helped pull survivors from wrecked cars, with some performing first aid.
"Several people offered us water and one man came out of his auto to give food". While others converse with cops about the misery of what has happened.
A representative stated: "We have 13 assets at the scene including the basic care group and the perilous range reaction group".
South Western Ambulance Service said it was called soon after 14.30 BST.
It included drivers the M4 wanting to join the M5 northbound were not able do as such.
It has cost them points for the second time this week, following the 2-2 draw with Sevilla in the Champions League. Dejan Loven has been ruled out with a back injury while Simon Mignolet returns in-goal for Liverpool .
Linebacker Brian Cushing is serving a 10-game suspension for violating the NFL's policy on performance-enhancing substances. He was under heavy pressure again Thursday while going 20 of 35 for 224 yards with three sacks and a passer rating of 76.4.
LSU (2-1, 0-1 SEC), which had two players ejected for targeting in a nine-penalty game, fell to State (3-0, 1-0 SEC), 37-7. LSU was without sophomore defensive end Rashard Lawrence, and appears to have lost sophomore nose tackle Ed Alexander.
It costs a lot of money to manufacture Kryptonite, but his value in building what's becoming a Clemson dynasty is priceless. Where the Tigers went wrong after halftime was giving Jackson too many opportunities, Clemson coach Dabo Swinney said.
He said he would love to have the Democrats working with the GOP "but we're going to do it no matter what". President Donald Trump says he wants to cut taxes to help middle-class Americans, not rich ones.
Anyone who showed up to the rally wearing masks or carrying other weapons would be arrested, police said. There is no such vote on the table in Richmond, which served as the Capital of the Confederacy.
Hollywood police Chief Tom Sanchez said investigators believe the deaths were heat-related. "It was very hot on the second floor". The bridge that crosses the river is just north of Gainesville, the state capital and home to the University of Florida .
Rudolph's success resulted in big numbers for the OSU receivers, as well, as four players tallied more than 100 receiving yards. The ninth-ranked Cowboys eventually had mercy, pulling Rudolph in the third quarter of an eventual 59-21 victory.
Kalsoom Nawaz has not taken part in the electioneering since she is under treatment for her cancer disease in London. It is the first time in Pakistan that biometric verification machines have been installed at 39 polling stations.
Some of the big tech companies that form a large part of the indexes offer above-average growth at reasonable valuations, he said. Additionally, North Korea threatened to reduce the U.S.to "ashes and darkness" and sink Japan, leaving the Nikkei in the red.
Stifel has invested 0% in Chesapeake Utilities Corporation (NYSE:CPK). 1,031 are owned by Northwestern Mutual Wealth Mngmt. Ladenburg Thalmann began new coverage on Chesapeake Utilities Corporation giving the company a "neutral" rating.
MI 29, Air Force 13
Quarterback Arion Worthmann had a big 34-yard run in the second quarter to tie the game up at 6-6 shortly before halftime. Michigan Wolverines defensive end Chase Winovich had a quote for the ages after defeating Air Force Saturday afternoon.